Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set V, EDTA-Free
A cocktail of four protease inhibitors for the inhibition of serine, cysteine, but not metalloproteases.
MilliporeSigma™ Calbiochem™ Wnt Agonist II, SKL2001
The Wnt Agonist II, SKL2001 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Raf Kinase Inhibitor IV
The Raf Kinase Inhibitor IV, also referenced under CAS 303727-31-3, controls the biological activity of Raf Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Xestospongin C, Xestospongia sp.
An oxaquinolizidine alkaloid isolated from a marine sponge.
MilliporeSigma™ Calbiochem™ Caspase-8 Inhibitor II
The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor III, WP1066
STAT3 Inhibitor III, WP1066, CAS 857064-38-1, is a cell-permeable AG490 tyrphostin analog that acts as a STAT3 pathway inhibitor. A potent anti-tumor agent.
MilliporeSigma™ Calbiochem™ Thrombin Substrate III, Fluorogenic
Sensitive fluorogenic substrate for the quantitative determination of thrombin.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor III
A cell-permeable benzothiazolylchromenone compound that disrupts Skp2-Skp1 interaction via direct Skp2 affinity binding and selectively prevents Skp2-, but not Fbw7- or β-TrCP-, Skp1-Cullin-1-F-box (SFC) complex-mediated substrates ubiquitination, effectively preventing Skp2 substrates activation (Akt) and degradation (p21 & p27) with concomitant down-regulation of cellular Skp2 protein level (10 to 20μM in HEK293T & PC3 cultures)
MilliporeSigma™ Calbiochem™ PP1 Analog IV, 3-IB-PP1
A cell-permeable enlarged PP1 analog that acts as a potent, ATP-competitive and reversible inhibitor of asAkt1/2/3.
MilliporeSigma™ Calbiochem™ ADP-HPD, Dihydrate, Ammonium Salt
ADP-HPD, Dihydrate is an amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM).
MilliporeSigma™ Calbiochem™ IDH2 Inhibitor, R140Q Somatic Mutant-Specific, AGI-6780
A cell-permeable inhibitor of isocitrate dehydrogenase 2 R140Q mutant-containing dimers. Has minimal effect on wild type dimer-catalyzed alpha-KG production.
MilliporeSigma™ Calbiochem™ Raf1 Kinase Inhibitor I
The Raf1 Kinase Inhibitor I, also referenced under CAS 220904-83-6, controls the biological activity of Raf1 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Apoptosis Activator VI, CD437/AHPN
The Apoptosis Activator VI, CD437/AHPN, also referenced under CAS 125316-60-1, modulates Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ 5-Fluorouracil
Potent antitumor agent.
MilliporeSigma™ Calbiochem™ Hypericin
Polycyclic dione that has anti-retroviral activity.